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Lexapro is a medication licensed as a means of treating depression and generalized anxiety disorder. Belonging to the group of medicaments known as SSRI (selective serotonin reuptake inhibitors), Lexapro blocks concentrations of serotonin in the brain. The medication is available in the forms of pills and liquid suspension. Lexapro is not recommended for use in children. Some typical side effects caused by Lexapro are nausea, migraine, insomnia.

What is Lexapro and What Is It Used for?

Lexapro® (escitalopram oxalate) is an antidepressant, prescribed in order to treat several brain disorders, including:

• Depression, which may also be called clinical or major depression
• GAD (generalized anxiety disorder).

Who Manufactures Lexapro?

Lexapro is made by Forest Pharmaceuticals.

In What Way Does Lexapro Work?

The drug belongs to the class of medications known as SSRI (selective serotonin reuptake inhibitors), influencing the work of serotonin (a certain chemical contained in the brain tissue). This chemical is responsible for transmitting messages between nerve cells.

Going down the nerve, the signal influences the cell, which releases serotonin. This chemical goes from one nerve cell to another, activating receptors on them, thus transmitting the message. Then the first cell absorbs the serotonin left between the nerve cells back. The process described is known as "reuptake".

As a rule, the process of reuptake goes normally. The depression and some other conditions occur when the amount of serotonin gets uneven. The medication stops the reuptake of the chemical and more of it stays between the nerve cells. Thus, the remaining amount of serotonin activates the receptors of adjacent nerve cells easier.

The clinical research of those patients who were taking Lexapro revealed its effectiveness in curing depression and GAD. It's proven that Lexapro may prevent depression relapse.

How Do I Take Lexparo?

When taking Lexapro, the following issues should be considered:

• The drug is available in the forms of pills and liquid suspension. You should take one dose a day by mouth.
• If a patient experiences drowsiness during the therapy with Lexapro, he's recommended to take it before going to bed. If, on the contrary, he's experiencing insomnia, he should take it in the morning.
• Lexapro can be taken either with or without food. In case of stomach discomfort, it's better to take it during a meal.
• You have to take the drug approximately at the same time every day to keep its level in blood flow even
• One should take the drug according to the prescription in order to maintain its proper work. The sudden stopping of medication use stops its effect.

Lexapro Dosage

You should dose the medication according to the recommendations of your therapist. The factors that may affect the recommended dosage are as follows:

• The age of the patient
• The disorders treated in a particular patient
• The presence or absence of other health disorders in a patient
• Some other drugs that the patient may take.

You should not regulate your dose without the therapist's instruction to do so.

Possible Side Effects of Therapy with Lexapro

Lexapro may cause some side effects, just like other medications may do. But not all the patients taking Lexapro will have them. However, in case of experiencing any of side effects, a patient won't necessarily require a special treatment, as he can be cured himself or with the help of therapist. Serious side effects of Lexapro are very rare.

Typical side effects of therapy with Lexapro are:

• Nausea
• Insomnia
• Migraine
• Extreme fatigue
• Problems with ejaculation.

Possible Drug Interactions with Lexapro

The drug is supposed to interact with a number of other substances and medications, among which are:

• Alcohol
• Aspirin
• Cimetidine (Tagamet®)
• Ketoconazole (Nizoral®)
• Linezolid (Zyvox®)
• Lithium (Eskalith®, Lithobid®)
• Metoprolol (Lopressor®, Toprol XL®)
• Monoamine oxidase inhibitors (MAOIs), including:

• Isocarboxazid (Marplan®)
• Phenelzine (Nardil®)
• Rasagiline (Azilect®)
• Selegiline (Eldepryl®, Emsam®, Zelapar®)
• Tranylcypromine (Parnate®)

• Nonsteroidal anti-inflammatory drugs (NSAIDs), such as:

• Ibuprofen (Motrin®, Advil®)
• Naproxen (Naprosyn®) or naproxen sodium (Aleve®, Anaprox®, Naprelan®)
• Diclofenac (Cataflam®, Voltaren®)
• Indomethacin (Indocin®)
• Nabumetone (Relafen®)
• Oxaprozin (Daypro®)
• Celecoxib (Celebrex®)
• Meloxicam (Mobic®)
• Etodolac (Lodine®)
• Ketoprofen (Orudis®)
• Ketorolac (Toradol®)

• Pimozide (Orap®)
• Other SSRI or SNRI antidepressants, such as:

• Citalopram (Celexa®)
• Duloxetine (Cymbalta®)
• Fluoxetine (Prozac®, Sarafem®)
• Paroxetine (Paxil®, Paxil CR®)
• Fluvoxamine (Luvox®)
• Sertraline (Zoloft®)
• Venlafaxine (Effexor®, Effexor XR®)

• St. John's wort
• Tramadol (Ultram®, Ultracet®)
• Tricyclic antidepressants, including:

• Amitriptyline (Elavil®)
• Amoxapine (Asendin®)
• Clomipramine (Anafranil®)
• Desipramine (Norpramin®)
• Doxepin (Sinequan®)
• Imipramine (Tofranil®)
• Maprotiline (Ludiomil®)
• Nortriptyline (Pamelor®)
• Protriptyline (Vivactil®)
• Trimipramine (Surmontil®)

• Triptans, including:

• Almotriptan (Axert®)
• Eletriptan (Relpax®)
• Frovatriptan (Frova®)
• Naratriptan (Amerge®)
• Rizatriptan (Maxalt®)
• Sumatriptan (Imitrex®)
• Zolmitriptan (Zomig®)

• Tryptophan
• Warfarin (Coumadin®, Jantoven®).

What Medical Conditions Can Serve as a Contra-Indication to Using Lexapro?

Let your therapist know if you have:

• Manic depression (family history or personal experience)
• A history of suicidal behavior or thoughts
• Recent heart attacks or heart disease which is unstable
• Diabetes
• Convulsion or epilepsy
• Disease of liver, including liver failure and cirrhosis
• Allergies (for instance, ones to food, dyes, preservatives).

Besides, inform the doctor if you are:

• Pregnant or trying to become pregnant
• Breastfeeding
• Consuming alcoholic drinks.

Tell your therapist about all other drugs you are taking. Let him know about all the prescribed and not prescribed medications, vitamins, and herbal medicaments.

Is There Any Alternative to Therapy with Lexapro?

Even an extreme form of depression can be cured. However, the earlier you start treating it, the more chances to recover you have.

The most typical means used in the treatment of depression are antidepressants, as well as psychotherapy (also known as "talk therapy"). Sometimes ECT (electroconvulsive therapy) is advised by the doctors if a patient suffers from a severe case of depression. It's also possible to try alternative ways of treating depression.

Many people taking the drug, admit the effectiveness of Lexapro. As a rule, Lexapro is well tolerated. But it still can cause some side effects and show lower effectiveness levels than expected. In case it happens, consult your doctor in order to get recommendations concerning the change of Lexapro for any of the drugs listed below:

• Other SSRIs
• SNRIs (serotonin-norepinephrine reuptake inhibitors)
• NDRIs (norepinephrine and dopamine reuptake inhibitors)
• Tricyclic antidepressants
• MAOIs (monoamine oxidase inhibitors).

What Should I Do in Case of Overdose with Lexapro?

If you took a larger dose of this medication you may experience the following symptoms:

• Giddiness
• Hypotension (low blood pressure)
• Drowsiness
• Insomnia
• Nausea or vomiting
• Tachycardia (rapid heart rhythm)
• Arrhythmia (uneven heart rhythm)
• Failure of kidney
• Convulsions
• Coma.

In case of overdose seek professional medical help immediately.

How Should I Store Lexapro?

Both forms of the drug (pills and liquid suspension) should be kept at room temperature in dry airtight container, away from children.

What Should I Do in Case I Miss a Dose of Lexapro?

If a patient forgets to take a dose of Lexapro on time, he should take it as soon as possible. However, if it is time for the next one already, he should skip the one he missed and continue taking the drug as scheduled. One should never take two doses.

Available Forms of Lexapro

The drug comes in the following strengths:

• Lexapro 5 mg
• Lexapro 10 mg
• Lexapro 20 mg.

The liquid form of the medication comes in one strength only: Lexapro® Oral Solution 5 mg per 5 mL (5 mg per teaspoonful).

Is Lexapro Available in the Form of a Generic Medication?

At the moment the drug is not available in generic form.

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