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Cozaar
Cozaar is a drug usually prescribed to the patients suffering from diabetic nephropathy as well as high blood pressure. This medication has not yet been proven to be able to fight either of these conditions though it is known to slow down the development of diabetic nephropathy and reduce blood pressure. Cozaar is available in the form of tablets of several different strengths. Most widespread minor side effects of this medication include dizziness, pain in the back and stuffy nose.
What Is Cozaar And What Is It Used for?
Cozaar® (generic name: losartan potassium) is a drug used in the treatment of several heart and blood vessels disorders. It belongs to a group of medications known under the common name of angiotensin II receptor blockers (also known as ARBs).
The conditions most often treated with Cozaar include:
- High blood pressure (hypertension)
- Diabetic nephropathy.
Cozaar is considered a remedy neither for high blood pressure nor diabetic nephropathy. It's safety of use in children from six years of age and older has been clinically proven.
Who Manufactures Cozaar?
The company manufacturing Cozaar is Merck & Co.
In What Way Does Cozaar Work?
Cozaar belongs to a class of medications referred to as angiotensin II receptor blockers.
As you can understand from the name this class of drugs is known under, the medications belonging to it can block angiotensin II receptors, which results in decreased effectiveness of angiotensin II, a chemical that makes blood vessels constrict (get narrow). Cozaar, on the contrary, makes blood vessels relax, which results in lowering of the patient's blood pressure.
How Effective Is Cozaar?
There are two numbers comprising a blood pressure reading – for instance, 120/80, the first of which is the systolic blood pressure index, and the second one – diastolic blood pressure index. During long-term clinical studies, Cozaar has been proven to be able to reduce systolic blood pressure in people taking it by up to 10.5 mmHg. It also reduced diastolic blood pressure by 3.5 to 7.5 mmHg in most of the cases. The results depend on a variety of factors – dosage, for instance.
The ability of Cozaar to reduce blood pressure helps the people avoid suffering from certain disorders associated with long-term high blood pressure – for instance, stroke and heart attack.
Cozaar has also been proven to slow down the development of diabetic nephropathy in people suffering from it, which consequently leads to less kidney damage and decreases the danger of development of potentially dangerous complications (including the need for kidney dialysis).
How Do I Take Cozaar?
This part of article about Cozaar comprises general advice on how it should be used.
- Cozaar is available in the form of tablets designed for peroral administration. Most patients are prescribed to take Cozaar once or twice each day.
- It doesn't matter whether you take Cozaar with or without food.
- Cozaar tablets are not to be broken, crushed or chewed unless a patient taking them is prescribed to do so by his healthcare provider.
- One of the keystones of therapy with Cozaar is that the patient taking it should adjust the intake schedule so that he or she takes it at around the same time each day, which helps to keep an even level of the active component in the blood flow.
- Follow your therapist's prescription in detail in order to ensure maximum effectiveness of Cozaar. This drug will stop working as soon as you stop taking it.
Cozaar Dosage
There are a significant number of factors that can affect the recommended dosage, the most important ones being:
- A particular health condition that Cozaar is used to treat
- Other disorders that a particular patient suffers from
- Simultaneous therapy with other drugs
- A particular patient's response to the effect of Cozaar.
Never risk trying to adjust your dose of Cozaar yourself – always let your healthcare provider do it for you.
Possible Side Effects of Therapy with Cozaar
There have been a number of side effects registered in people taking Cozaar. However, it should be noticed that just a tiny fraction of people taking Cozaar reported suffering from side effects since most of them are minor ones and either don't require treating at all or can easily be cured by the patient himself or his or her healthcare provider. Serious side effects of Cozaar are observed very rarely.
Most widespread side effects experienced by the patients treating high blood pressure with Cozaar are as follows:
- Infection, including common cold or influenza
- Dizziness
- Stuffy nose
- Pain in the back.
The patients taking Cozaar as a remedy for diabetic nephropathy may experience such side effects as:
- Diarrhea
- Extreme fatigue
- Anemia
- Increased blood potassium levels
- Decreased blood pressure
- Weight gain.
Possible Drug Interactions with Cozaar
Below is the list of medications and other substances that Cozaar may interact with.
- torsemide (Demadex®)
- furosemide (Lasix®)
- hydrochlorothiazide, etc
- Potassium-rich supplements and salt substitutes containing potassium
- Potassium-sparing diuretics, such as:
- spironolactone (Aldactone®)
- triamterene (Dyrenium®)
- amiloride (Midamor®), etc
- Rifampin (Rifadin®, Rimactane®, Rofact®)
- Lithium (Eskalith®, Lithane®, Lithonate®, Lithotabs®)
- Nonsteroidal anti-inflammatory drugs (NSAIDs), such as:
- ibuprofen (Motrin®, Advil®)
- naproxen (Naprosyn®)
- naproxen sodium (Aleve®, Anaprox®, Naprelan®)
- diclofenac (Cataflam®, Voltaren®)
- indomethacin (Indocin®)
- nabumetone (Relafen®)
- oxaprozin (Daypro®)
- celecoxib (Celebrex®)
- meloxicam (Mobic®)
- etodolac (Lodine®)
- ketoprofen, ketorolac (Toradol®), etc
What Medical Conditions Can Serve as a Contra-Indication to Using Cozaar?
Before you start the therapy with Cozaar, let your therapist know if you have:
- Heart disease (congestive heart failure among others)
- Liver disease (cirrhosis, etc)
- Kidney disease or a history of renal failure
- Diabetes
- Allergies, including allergy to certain angiotensin II receptor blockers, foods, food colorings, or preservatives.
Don't forget to tell your therapist if you:
- Are pregnant or attempting to get pregnant
- Are on dialysis
- Are breastfeeding a baby.
You are also recommended to inform your therapist about all other prescription and non-prescription medicines, herbal supplements as well as vitamins that you are taking at the moment.
Potassium-rich supplements and potassium salt substitutes are known to interact with Cozaar, so make sure you don't take any unless your therapist allows you to.
What Should I Do in Case of Overdose with Cozaar?
Cozaar overdose is known to be able to cause serious conditions, among which are extreme drop of blood pressure and increased heart rate.
In case you think you might have taken too much Cozaar, seek emergency medical attention immediately.
How Should I Store Cozaar?
Cozaar is to be stored at room temperature without being exposed to excess moisture and heat, preferably in an airtight container. The place where Cozaar is kept should also be located out of the reach of children.
What Should I Do in Case I Miss a Dose of Cozaar?
If you fail to take a dose of Cozaar in accordance with your schedule, take it as soon as remembered unless the time for the next dose has almost come already – in this case skip the missed dose and keep on with your usual intake schedule. Never double the dose!
Available Forms of Cozaar
Cozaar is available in tablet form with several strengths being offered, namely:
- Cozaar 25 mg
- Cozaar 50 mg
- Cozaar 100 mg.
Is Cozaar Available in the Form of a Generic Medication?
There is no generic Cozaar licensed for sale at the moment.
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