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Ativan
Ativan is a medication which is produced in the form of pills, oral liquid and injections and is prescribed for the treatment of anxiety. Its curing effect is based on its ability to work in the brain tissue prompting the effect of naturally calming brain chemical - gamma-aminobutyric acid (GABA). As any drug it is not spared of side effects. Among the possible ones there are dizziness, weakness and unsteadiness.
What Is Ativan And What Is It Used for?
Ativan® (lorazepam), belonging to the group of benzodiazepines, is a drug available by prescription and used in anxiety treatment. It comes out in the form of pills, oral liquid and injections, with the latter being a medicine used for decreasing anxiety, nervous tension and curing severe seizures (status epilepticus).
Who Manufactures Ativan?
Ativan is now manufactured by Biovail Pharmaceuticals.
In What Way Does Ativan Work?
Belonging to the group of benzodiazepines, Ativan has the following effects on the human body, common for all the members of this group of drugs:
- it reduces anxiety
- it causes sleepiness
- it produces relaxing effect on muscles
- it stops seizures
- it impairs short-term memory.
Any of benzodiazepines has the same effects, though the extent of them varies from drug to drug. They also affect the brain tissue by prompting the effect of naturally calming brain chemical - gamma-aminobutyric acid (GABA), which has the ability to block or reduce the speed of certain nerve signals passed by brain cells. This effect explains why benzodiazepines have also acquired the name of sedatives, or mild tranquilizers, or central nervous system depressants (CNS depressants).
How Do I Take Ativan?
The following are the general instructions on how Ativan should be taken if prescribed:
- Ativan is produced in three different forms (pills, oral liquid and injections). If you've been prescribed Ativan for oral intake, you'd most probably be recommended to take it two or three times a day. There're also cases when it is prescribed to be taken once, before bedtime.
- The Ativan intake is not food-dependant, but if it causes you any sort of stomach discomfort, try taking it along with meals.
- Do not violate the intake rules set up by your prescription. Overdose or taking Ativan longer than is prescribed by your healthcare provider might cause serious problems.
Ativan Dosage
Your healthcare provider will set up the dosage for you, and that will depend on a number of factors:
- Your age
- Whether you do or do not take any other medications
- Whether you do or do not have any other health disorders.
You are not recommended to change the dosing scheme unless you're told to do so by your healthcare provider.
Possible Side Effects of Therapy with Ativan
As any other drug Ativan is not free of side effects, though they do not always accompany the Ativan intake. Moreover, the majority of patients undergoing the Ativan therapy do not encounter any problems, and even if the side effects occur, they take minor forms and can be easily cured by the patient himself or with the help of his healthcare provider. Serious side effects are fewer and less frequently encountered. The following list shows the most common side effects of Ativan:
- Sedation (a sleeping or calming effect)
- Dizziness
- Weakness and fatigue
- Unsteadiness
- Hair loss
- Increased appetite and, consequently, getting on weight.
Possible Drug Interactions with Ativan
Ativan® (lorazepam) in the course of the therapy might interact with a certain number of other medications and substances, which are as follows:
- Substances containing alcohol
- Anesthetics
- Antidepressantmedications
- Antipsychotic medications, such as:
- Aripiprazole (Abilify®)
- Chlorpromazine(Thorazine®)
- Clozapine (Clozaril®, FazaClo®)
- Fluphenazine (Prolixin®)
- Olanzapine (Zyprexa®, Symbyax®)
- Perphenazine (Trilafon®)
- Paliperidone (Invega®)
- Quetiapine (Seroquel®)
- Risperidone (Risperdal®)
- Thioridazine (Mellaril®)
- Trifluoperazine (Stelazine®)
- Ziprasidone (Geodon®)
- Amobarbital (Amytal®)
- Butalbital (Fioricet®, Fiorinal®)
- Pentobarbital (Nembutal®)
- Phenobarbital (Luminal®)
- Secobarbital (Seconal®)
- Divalproex sodium (Depakote®, Depakote ER®, or valproic acid (Depakene®)
- Narcotics or opiates, such as morphine, oxycodone (OxyContin®), or hydrocodone (Lortab®, Vicodin®)
- Other benzodiazepines, including:
- Alprazolam (Xanax®)
- Chlordiazepoxide (Librium®, Limbitrol®, Librax®)
- Clonazepam (Klonopin®)
- Clorazepate (Tranxene®)
- Diazepam (Valium®)
- Estazolam (ProSom®)
- Flurazepam (Dalmane®)
- Midazolam (Versed®)
- Temazepam (Restoril®)
- Triazolam (Halcion®)
- Probenecid
- Seizure medications
- Sleep medications.
What Medical Conditions Can Serve as a Contra-Indication to Using Ativan?
Before taking Ativan do not forget to mention it to you healthcare provider if you have any of the following medical conditions:
- Glaucoma
- Alcohol or drug addiction in the past
- Depression
- Liver disease, cirrhosis or liver failure
- Kidney disease, kidney failure (renal failure)
- Allergies of any type, like allergies to food, dyes, or preservatives.
Also talk to your healthcare provider if you are:
- Pregnant or thinking about getting pregnant
- Breastfeeding a baby.
Do not forget to tell your healthcare provider about any other drugs you take, controlled or over-the-counter ones, including such substances as vitamins or herbal supplements.
What Should I Do in Case of Overdose with Ativan?
The Ativan overdose may be defined by the following symptoms:
- Sedation
- Coma
- Speech disorders
- Lethargy
- Confusion
- Hypotension (low blood pressure)
- Breathing dysfunction
- Lethal effect.
In case of overdose you should immediately call for professional medical help.
What Should I Do in Case I Miss a Dose of Ativan?
If you happen to have missed a dose of Ativan, take one as soon as you remember, unless it is already time for the next dose. In this case skip the dose you have missed and go on taking Ativan as prescribed. Never double the dose of Ativan wishing to catch up for the missed dose.
What Strengths of Ativan Are Available?
Ativan is available in three strengths:
- Ativan 0.5 mg
- Ativan 1 mg
- Ativan 2 mg.
It is also available in two more forms – that of oral liquid and that of injections.
Is Ativan Available in the Form of a Generic Medication?
Both the licensed brand-name version and Ativan in the form of generic medication are currently sold.
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